Seminar on How can engineered organs be designed to improve physiological function?
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Prof Qi GU Beijing Institute for Stem Cell and Regenerative Medicine Institute of Zoology, Chinese Academy of Sciences This seminar will be chaired by Prof Yeong Wai Yee. |
Seminar Abstract |
The field of organ fabrication, integrating developmental biology with bioinspired engineering, strives to replicate the intricate structures and functions of natural organs, marking a significant advancement in tissue engineering. Traditional methods like advanced 3D bioprinting allow for the creation of cellular constructs with specific architectures, but the complexity of organ development—including unique cellular movements and arrangements—poses substantial challenges. This research explores strategies to design and engineer organs that enhance physiological function, examining how these fabricated organs can more closely mirror their natural counterparts in both structural and functional properties. By focusing on microphysiological function simulations, we assess this concordance and address the gap between engineered constructs and natural organs through innovative approaches. This presentation provides insights from recent projects in our laboratory, highlighting the challenges and disparities in simulating physiological functions and exploring novel methods to narrow the gap between artificial and natural organs. Our goal is to advance the field of organ manufacturing, bringing us closer to achieving fully functional, bioengineered organs that more accurately emulate physiological functions.. |
Speaker's Biography |
Dr. Gu, currently a Full Professor at both the Beijing Institute for Stem Cell and Regenerative Medicine and the Institute of Zoology, Chinese Academy of Sciences. He spearheads a laboratory renowned for its advancements in biomaterials and cutting-edge technologies, notably 3D/4D bioprinting. As an accomplished academic, Dr Gu has published over 40 peer-reviewed articles in prestigious journals, including but not limited to Adv. Mater., Angew. Chem. Int. Ed., Biomaterials, Mater. Horiz. and Adv. Funct. Mater., primarily delving into bioprinting, biofabrication, and stem cell engineering. In acknowledgment of his significant contributions to the field, he has been honored with the Young Investigator Award from the Chinese Society of Stem Cell Research (CSSCR), and awarded Australia China Alumni Award for Research and Science in 2023 from Australia China Alumni Association and the Excellent Young Scientists Fund from the National Natural Science Foundation of China (NSFC). Beyond research, he lends his expertise to the editorial boards of esteemed journals, such as Biofabrication, Bioactive Materials, and IJAMD. |