Manual inverted fluorescence, Olympus IX73 patch clamp system

Ion channel screening capabilities

EMB #03-02X

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70+ ION CHANNEL & TRANSPORTER CELL LINES 

• Voltage-gated potassium channels
• Calcium-activated potassium channels
• Inward-rectifier potassium channels
• Two-pore domain potassium channels
• Sodium channels
• Calcium channels
• TRP channels
• Acid-sensitive ion channels
 		• Chloride channels
• Hyperpolarisation-activated cyclic
nucleotide-gated ion channels
• GABA
• NMDA
• Ach
• 5-HT
 

We provide high-quality patch clamp analysis for non-clinical cardiac safety assessment according to the recommendations of Comprehensive in vitro Proarrhythmia (CiPA) initiative, a new strategy proposed by FDA and other expert working groups such as the Health and Environmental Sciences Institute (HESI) and Cardiac Safety Research Consortium (CSRC).

We also perform pharmacology screening of ion channel modulators.

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