A key research focus for FRESH is the development and validation of human-relevant, non-animal models for food safety testing. Our methodologies include:

• in vitro toxicology
• in silico toxicology
• in vitro digestion

FRESH reviews the application of risk assessment methodologies in other industry sectors to learn how they can be adapted to the novel food framework in Singapore. We are particularly interested in:

• Next generation risk assessment (NGRA) frameworks
• Benefit-risk assessment
• Quantitative risk assessment of allergens