Biomolecular Interactions

The Biomolecular Interactions (BMI) Platform in BioSciences Research Centre (BRC), School of Biological Sciences, at NTU Singapore offers access to a spectrum of biophysical techniques to help users characterize molecules of research and interest. The techniques at BMI platform are suitable for protein to protein or DNA / ligand / small molecules / hormones / fragments interactions; molecular mass and size measurements, secondary/tertiary structure determination, aggregation, and conformation measurements, and more.

The BMI platform offers scientific consultation, training, and access to the following technologies housed at SBS, NTU:

  • Surface Plasmon Resonance Interaction Assays on a Biacore T200.
  • Biolayer Interferometry assays on Gator Prime.
  • Isothermal Calorimetry on a Malvern ITC200.
  • Mass photometry on a Refeyn TwoMP.
  • Dynamic Light Scattering and Zeta potential analysis on a Malvern Zetasizer ZS Nano.
  • Circular Dichroism measurements on a Chirascan CD Spectrometer.
  • Fluorescence measurements on a Cary Eclipse Fluorescent Spectrophotometer.
  • Analytical Ultra-Centrifugation on a Beckman Proteomelab-XL.

For more information, visit Biomolecular Interactions page