DESCRIPTION OF LAB RESEARCH WORK
The research of our lab focuses on developing biomolecular modeling approaches and the related applications in computational biophysics. In particular, we are interested in designing and adopting state-of-the-art simulation techniques to understand abundant experimental data in structural biology.

The main research directions are:

• The methodological advances of multiscale coarse-graining methods and new approaches for elastic network models and structure-based protein models;
• Developing atomistic and coarse-grained models to simulate multi-domain proteins and protein-protein interactions;
• Novel algorithms for modeling solution X-ray scattering of proteins;
• Ensemble structure determination by using combined experimental (nuclear magnetic resonance or small angle X-ray scattering) and molecular simulation data;
• Using molecular simulation to interpret experimental information in structural biology (e.g., Cryo-electron microscopy, single molecule experiment, etc.).