X-Ray Diffraction Laboratory
The X-Ray Diffraction Lab operates three state-of-the-art Bruker single crystal diffractometers. We serve the educational and research needs of the students and researchers within NTU by providing structure determination of single crystal samples, training new users, and offering advice and technical assistance in crystal growth, data collection, structure refinement and data interpretation. We also provide access to the Cambridge Structure Database (CSD).
Users from outside the university are also welcome.
Sample Submission
All samples must be accompanied by a completed sample submission form below:
Samples should be kept in a sealed vial and in mother liquor if possible.
User Training
The lab holds group trainings for students and researchers to use the instrument and the APEX 3 software suite for processing diffraction data. Users are encouraged to attend the training and obtain the licence to operate the Bruker X8 Apex diffractometer.
Contact Information
Li Yongxin (Dr), Lab manager and Crystallographer
Email: [email protected]
Office phone: +65-63168843
Lab location: SPMS-CBC-01-18E, 21 Nanyang Link, Singapore 637371
Equipment List
Bruker X8 APEX
The Bruker X8 Apex instrument was installed in 2005. It is equipped with an Oxford Cryostream series 800 variable temperature unit providing sample temperature from 90 to 400K. It operates with a fine focus sealed tube Mo X-ray source and an APEX II CCD detector. This instrument is mainly for training and student projects.
Bruker KAPPA APEX Duo
The Bruker KAPPA APEX Duo was purchased in 2009 as a fine focus sealed tube mono Mo source diffractometer. It was upgraded in 2016 to a duo source system by adding an Incoatec high brilliance IμS 2.0 Cu microfocus source. The system is equipped with an Oxford Cryostream series 700 variable temperature device with the sample temperature ranging from 90 to 400K and the detector is also an Apex II CCD detector. This Kappa Apex Duo is featuring to determine absolute configurations of organic compounds containing atoms not heavier than Si.
Bruker D8 Quest
This Bruker D8 Quest was installed in 2017. It is equipped with an Incoatec IμS 3.0 Mo microfocus X-ray source and a large area PHOTON II CPADs detector. This advanced system allows for the detector to collect X-ray diffraction data continuously in shutterless mode leading to substantially short data collection times. The equipped Oxford Cryostream series 800 variable temperature unit enables the data collection at a temperature range of 90-400K. This system is for routing structure determination of small molecules including organic, inorganic and organometallic compound as well as alloys.
Polarizing Microscope
The lab houses an Olympus SZX2 polarizing microscope coupled with an Olympus DP73 digital camera for crystal selecting and mounting.
Resources
- Growing Crystals that will Make Your Crystallographer Happy by P.D Boyle from West University, Canada.
- Crystal Growing Tips and Methods by B.C Manor & P.J Carroll from University of Pennsylvania.
- SHELX Homepage – general information about the SHELX system of crystallographic programs and how to obtain them.
- Mercury from CCDC – a comprehensive range of tools for 3D structure visualization, the exploration of crystal packing and the statistical analysis of CSD search data.
- Platon Homepage – a multipurpose crystallographic tool.